ชุดเก็บสิ่งส่งตรวจสําหรับสตรีเพื่อตรวจหาเชื้อ HPV

รายละเอียดเพิ่มเติม

Nearly 100% of cervical cancer is caused by HPV (Human papillomavirus) and up to 85% of the population (both men and women) had been infected with HPV once in their lifetime

Cervical cancer in Thai women

The third most common cancer

New diagnosed cases of cervical cancer per year

Number of deaths from cervical cancer

Cervical cancer screening test

There are 3 cervical cancer screening tests as table below

Test

What to detect?

Comment

Pap test (Pap smear)

Cervical cell changes
(abnormal cell appearance)

Old method

HPV DNA test

High-risk HPV (that causes cervical cancer)

More sensitivity

Co-testing

Both (high-risk HPV and cervical cell changes)

More sensitivity

*The largest prospective trial to evaluate Pap and HPV DNA screening test strategies that enrolled over 47,000 women, ATHENA study shows significantly more sensitive detecting precancerous lesion

“HPV self-sampling improves screening for cervical cancer”

In 2021, World Health Organization (WHO) had launched a new guideline for cervical cancer prevention that suggested using HPV DNA test as primary screening test by using either samples taken by a health-care provider or self-collected samples. Some research shows a cervical screening test using a self-collected sample is just as accurate at detecting HPV as a clinician-collected sample during a pelvic examination

How to collect?

References

National Cancer Institute [Internet]. HPV and cancer. [updated 2021 Oct 25; cited 2022 May 28]. Available from https://www.cancer.gov/about-cancer/causes-prevention/risk/infectious-agents/hpv-and-cancer
Centers of Disease control and Prevention [Internet]. Reasons to get HPV vaccine. [updated 2021 Nov 10; cited 2022 Jun 20]. Available from https://www.cdc.gov/hpv/parents/vaccine/six-reasons.html
International Agency for Research on Cancer (World Health Organization) [Internet]. Thailand fact sheets (Globocan2020). [updated 2022 Mar 28; cited 2022 May 28]. Available from: https://gco.iarc.fr/today/data/factsheets/populations/764-thailand-fact-sheets.pdf
Wright TC, Stoler MH, Behrens CM, Sharma A, Zhang G, Wright TL. Primary cervical cancer screening with human papillomavirus: end of study results from the ATHENA study using HPV as the first-line screening test. Gynecol Oncol. 2015;136(2):189-97.
World Health Organization (WHO). WHO guideline for screening and treatment of cervical pre-cancer lesions for cervical cancer prevention, second edition. Geneva: World Health Organization; 2021.
Polman NJ, Ebisch RMF, Heideman DAM, Melchers WJG, Bekkers RLM, Molijn AC, et al. Performance of human papillomavirus testing on self-collected versus clinician-collected samples for the detection of cervical intraepithelial neoplasia of grade 2 or worse: a randomised, paired screen-positive, non-inferiority trial. Lancet Oncology. 2019 Feb;20(2):229-238.

รายละเอียดเพิ่มเติม

Nearly 100% of cervical cancer is caused by HPV (Human papillomavirus) and up to 85% of the population (both men and women) had been infected with HPV once in their lifetime

Cervical cancer in Thai women

Cervical cancer screening test

“HPV self-sampling improves screening for cervical cancer”

How to collect?

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